ZFYVE21 抗体 (N-Term)
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北京 101111
Quick Overview for ZFYVE21 抗体 (N-Term) (ABIN6991717)
抗原
See all ZFYVE21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- At least two isoforms of ZF21 are known to exist, this antibody will detect both isoforms.
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纯化方法
- ZF21 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ZF21 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZF21. The immunogen is located within the first 50 amino acids of ZF21.
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亚型
- IgG
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anti-Zinc Finger, FYVE Domain Containing 21 (ZFYVE21) (N-Term) antibody
ZFYVE21 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 21 (ZFYVE21) (AA 1-234) antibodyZFYVE21 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 21 (ZFYVE21) (AA 99-148) antibodyZFYVE21 适用: 人, 大鼠, 马, 兔, 斑马鱼, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 21 (ZFYVE21) antibodyZFYVE21 适用: 人 WB 宿主: 小鼠 Monoclonal 2B12 unconjugated
anti-Zinc Finger, FYVE Domain Containing 21 (ZFYVE21) (Middle Region) antibodyZFYVE21 适用: 人, 大鼠, 小鼠, 马, 兔, 斑马鱼, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 21 (ZFYVE21) (N-Term) antibodyZFYVE21 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ZF21 antibody can be used for detection of ZF21 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ZF21 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ZF21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))
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别名
- ZF21
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背景
- ZF21 Antibody: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.
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基因ID
- 79038
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NCBI登录号
- NP_001185882
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UniProt
- Q9BQ24
抗原
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