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ZFYVE21 抗体 (N-Term)

This anti-ZFYVE21 antibody is a 兔 多克隆 antibody detecting ZFYVE21 in WB, ELISA 和 IF. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6991717
发货至: 中国

Quick Overview for ZFYVE21 抗体 (N-Term) (ABIN6991717)

抗原

See all ZFYVE21 抗体
ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

适用

  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 4
  • 3

克隆类型

  • 6
  • 1
多克隆

标记

  • 7
This ZFYVE21 antibody is un-conjugated

应用范围

  • 7
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    N-Term

    特异性

    At least two isoforms of ZF21 are known to exist, this antibody will detect both isoforms.

    纯化方法

    ZF21 Antibody is affinity chromatography purified via peptide column.

    免疫原

    ZF21 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZF21. The immunogen is located within the first 50 amino acids of ZF21.

    亚型

    IgG
  • 应用备注

    ZF21 antibody can be used for detection of ZF21 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ZF21 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ZF21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ZFYVE21 (Zinc Finger, FYVE Domain Containing 21 (ZFYVE21))

    别名

    ZF21

    背景

    ZF21 Antibody: ZF21 was initially identified as protein that could bind to the cytoplasmic tail of MT1-MMP (Membrane-type 1 matrix metalloproteinase), a potent invasion-promoting protease. ZF21 is a member of a protein family characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain and regulates focal adhesions (FAs) and cell movement. Knockdown of ZF21 expression resulted in a delay of FA disassembly following induction of synchronous disassembly of FAs by nocodazole treatment, suggesting that ZF21 is involved in FA disassembly. ZF21 contains a noncanonical pleckstrin homology domain that is a possible therapeutic target to treat metastatic cancer.

    基因ID

    79038

    NCBI登录号

    NP_001185882

    UniProt

    Q9BQ24
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