PHOX2B 抗体 (AA 130-180)
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北京 101111
Quick Overview for PHOX2B 抗体 (AA 130-180) (ABIN6991707)
抗原
See all PHOX2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-180
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特异性
- PHOX2B antibody is predicted to not cross-react with other paired homeobox family members.
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纯化方法
- PHOX2B Antibody is affinity chromatography purified via peptide column.
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免疫原
- PHOX2B antibody was raised against a 15 amino acid synthetic peptide near the center of human PHOX2B. The immunogen is located within amino acids 130 - 180 of PHOX2B.
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亚型
- IgG
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anti-Paired-Like Homeobox 2b (PHOX2B) (AA 104-130) antibody
PHOX2B 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal RB28842 unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) (AA 104-130) antibodyPHOX2B 适用: 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) antibodyPHOX2B 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) (AA 1-90) antibodyPHOX2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) antibodyPHOX2B 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) (Internal Region) antibodyPHOX2B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) (N-Term) antibodyPHOX2B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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PHOX2B antibody can be used for detection of PHOX2B by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PHOX2B Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PHOX2B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
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别名
- PHOX2B
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背景
- PHOX2B Antibody: PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons.
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基因ID
- 8929
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NCBI登录号
- NP_003915
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UniProt
- Q99453
抗原
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