LEMD2 抗体 (AA 220-270)
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Quick Overview for LEMD2 抗体 (AA 220-270) (ABIN6991701)
抗原
See all LEMD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-270
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特异性
- At least two isoforms of LEMD2 are known to exist, this antibody will detect only the longer isoform.
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纯化方法
- LEMD2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- LEMD2 antibody was raised against a 16 amino acid synthetic peptide near the center of human LEMD2. The immunogen is located within amino acids 220 - 270 of LEMD2.
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亚型
- IgG
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anti-LEM Domain Containing 2 (LEMD2) (AA 17-204) antibody
LEMD2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-LEM Domain Containing 2 (LEMD2) (AA 431-480) antibodyLEMD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-LEM Domain Containing 2 (LEMD2) (C-Term) antibodyLEMD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-LEM Domain Containing 2 (LEMD2) (Middle Region) antibodyLEMD2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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LEMD2 antibody can be used for detection of LEMD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LEMD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- LEMD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- LEMD2 (LEM Domain Containing 2 (LEMD2))
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别名
- LEMD2
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背景
- LEMD2 Antibody: The LEM (lamina-associated polypeptide-emerin-MAN1) domain is a motif shared by a group of lamin-interacting proteins of the inner nuclear membrane (INM) and nucleoplasm. One such protein, LEMD2 (LEM domain-containing protein 2), is a lamina-associated protein in the INM involved in nuclear structure organization, containing an N-terminal LEM motif, two transmembrane domains, and a MAN1-Src1p C-terminal (MSC) domain. LEMD2 is a truncated paralog of MAN1, lacking the MAN1-specific C-terminal RNA-recognition motif, but like MAN1 is required for myogenic differentiation. Mutations in LEMD2 are thought be among the possible causes of muscle disease.
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基因ID
- 221496
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NCBI登录号
- NP_851853
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UniProt
- Q8NC56
抗原
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