TTYH2 抗体 (N-Term)
This anti-TTYH2 antibody is a 兔 多克隆 antibody detecting TTYH2 in ELISA, WB, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for TTYH2 抗体 (N-Term) (ABIN6991699)
抗原
See all TTYH2 抗体
TTYH2
(Tweety Homolog 2 (TTYH2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This TTYH2 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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抗原表位
- AA 60-110, N-Term
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特异性
- At least four isoforms of TTYH2 are known to exist, this antibody will only detect the two longest isoforms. This antibody is predicted to not cross-react with other TTYH family members.
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纯化方法
- TTYH2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TTYH2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human TTYH2. The immunogen is located within amino acids 60 - 110 of TTYH2.
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亚型
- IgG
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anti-Tweety Homolog 2 (TTYH2) (AA 455-534) antibody
TTYH2 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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TTYH2 antibody can be used for detection of TTYH2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TTYH2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TTYH2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TTYH2 (Tweety Homolog 2 (TTYH2))
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别名
- TTYH2
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背景
- TTYH2 Antibody: TTYH2 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH2 is a Ca2+-activated large conductance chloride (Cl-) channel and may play a role in kidney tumorigenesis. It is also upregulated in colon carcinoma and is thought to play a role in cell proliferation and call aggregation, suggesting that TTYH2 may play a role in regulating both proliferation and metastatic potentials of colorectal cancer. The ubiquitin-protein ligase Nedd4-2 binds to and ubiquitinates TTYH2, thereby regulating its cell surface expression and total cellular levels.
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基因ID
- 94015
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NCBI登录号
- NP_116035
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UniProt
- Q9BSA4
抗原
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