ZNF521 抗体 (N-Term)
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北京 101111
Quick Overview for ZNF521 抗体 (N-Term) (ABIN6991692)
抗原
See all ZNF521 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- ZNF521 antibody is human specific.
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纯化方法
- ZNF521 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ZNF521 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZNF521. The immunogen is located within the first 50 amino acids of ZNF521.
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亚型
- IgG
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应用备注
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ZNF521 antibody can be used for detection of ZNF521 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ZNF521 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ZNF521 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ZNF521 (Zinc Finger Protein 521 (ZNF521))
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别名
- ZNF521
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背景
- ZNF521 Antibody: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
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分子量
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Predicted: 144 kDa
Observed: 145 kDa -
基因ID
- 25925
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NCBI登录号
- NP_056276
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UniProt
- Q96K83
抗原
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