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PHOX2A 抗体 (C-Term)

This anti-PHOX2A antibody is a 兔 多克隆 antibody detecting PHOX2A in WB, ELISA, IF 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6991686
发货至: 中国

Quick Overview for PHOX2A 抗体 (C-Term) (ABIN6991686)

抗原

See all PHOX2A 抗体
PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PHOX2A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    特异性

    PHOX2A antibody is predicted to not cross-react with other paired homeobox family members.

    纯化方法

    PHOX2A Antibody is affinity chromatography purified via peptide column.

    免疫原

    PHOX2A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PHOX2A. The immunogen is located within the last 50 amino acids of PHOX2A.

    亚型

    IgG
  • 应用备注

    PHOX2A antibody can be used for detection of PHOX2A by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PHOX2A Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    PHOX2A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

    别名

    PHOX2A

    背景

    PHOX2A Antibody: PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons.

    基因ID

    401

    NCBI登录号

    NP_005160

    UniProt

    O14813
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