CP110 抗体 (C-Term)
CCP110
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all CP110 (CCP110) 抗体
- CP110 (CCP110) (Centriolar Coiled Coil Protein 110kDa (CCP110))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CP110 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- Two isoforms of CCP110 are known to exist, this antibody will only detect the longer isoform
- 纯化方法
- CCP110 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- CCP110 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human CCP110. The immunogen is located within the last 50 amino acids of CCP110.
- 亚型
- IgG
- Top Product
- Discover our top product CCP110 Primary Antibody
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anti-Centriolar Coiled Coil Protein 110kDa (CCP110) (AA 51-284) antibody
CCP110 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centriolar Coiled Coil Protein 110kDa (CCP110) (N-Term) antibodyVerified CCP110 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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CCP110 antibody can be used for detection of CCP110 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- CCP110 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- CCP110 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- CP110 (CCP110) (Centriolar Coiled Coil Protein 110kDa (CCP110))
- 别名
- CCP110 (CCP110 产品)
- 别名
- 6330503K22Rik antibody, AA415922 antibody, AI427129 antibody, AW557948 antibody, CP110 antibody, Cep110 antibody, Cp110 antibody, RGD1310509 antibody, centriolar coiled coil protein 110 antibody, centriolar coiled-coil protein 110 antibody, Ccp110 antibody, CCP110 antibody
- 背景
- CCP110 Antibody: CCP110 is a centrosomal protein required for the centrosome to function as a microtubule organizing center and plays an essential role in centrosome duplication. It is a target of cyclin-dependent kinases (CDKs), disruption of CCP110 phosphorylation leads to unscheduled centrosome separation and polyploidy. CCP110 is also a target of SCF (Cyclin F) ubiquitin ligase complex, leading to its degradation, suggesting that this complex controls centrosome homeostasis and mitotic fidelity through CCP110 degradation. The centriolar kinesin Kif24 also interacts with CP110 and remodel microtubules and regulate ciliogenesis.
- 分子量
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Predicted: 110 kDa
Observed: 110 kDa - 基因ID
- 9738
- NCBI登录号
- NP_001185951
- UniProt
- O43303
- 途径
- M Phase
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