Nicalin 抗体 (C-Term)
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Quick Overview for Nicalin 抗体 (C-Term) (ABIN6991672)
抗原
See all Nicalin (NCLN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 390-440, C-Term
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纯化方法
- NCLN Antibody is affinity chromatography purified via peptide column.
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免疫原
- NCLN antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human NCLN. The immunogen is located within amino acids 390 - 440 of NCLN.
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亚型
- IgG
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anti-Nicalin (NCLN) (AA 44-144) antibody
NCLN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nicalin (NCLN) (N-Term) antibodyNCLN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nicalin (NCLN) (AA 214-522) antibodyNCLN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nicalin (NCLN) (C-Term) antibodyNCLN 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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NCLN antibody can be used for detection of NCLN by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NCLN Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NCLN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Nicalin (NCLN)
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别名
- NCLN
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背景
- NCLN Antibody: Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-β, superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer's disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.
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基因ID
- 56926
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NCBI登录号
- NP_064555
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UniProt
- Q969V3
抗原
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