SIGLEC15 抗体 (N-Term)
This anti-SIGLEC15 antibody is a 兔 多克隆 antibody detecting SIGLEC15 in ELISA, WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
Quick Overview for SIGLEC15 抗体 (N-Term) (ABIN6991662)
抗原
See all SIGLEC15 抗体
SIGLEC15
(Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This SIGLEC15 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 50-100, N-Term
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特异性
- SIGLEC15 antibody is predicted to not cross-react with other SIGLEC family members.
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纯化方法
- SIGLEC15 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SIGLEC15 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SIGLEC15. The immunogen is located within amino acids 50 - 100 of SIGLEC15.
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亚型
- IgG
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anti-Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 274-302), (C-Term) antibody
SIGLEC15 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB29353 unconjugated
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应用备注
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SIGLEC15 antibody can be used for detection of SIGLEC15 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SIGLEC15 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SIGLEC15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
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别名
- SIGLEC15
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背景
- SIGLEC15 Antibody: Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.
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分子量
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Predicted: 36 kDa
Observed: 42 kDa -
基因ID
- 284266
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NCBI登录号
- NP_998767
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UniProt
- Q6ZMC9
抗原
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