C9ORF116 抗体 (N-Term)
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北京 101111
Quick Overview for C9ORF116 抗体 (N-Term) (ABIN6991649)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- PIERCE1 antibody is predicted to not cross-react with other UPF0691 family members.
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纯化方法
- PIERCE1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PIERCE1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human PIERCE1. The immunogen is located within the first 50 amino acids of PIERCE1.
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亚型
- IgG
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anti-Chromosome 9 Open Reading Frame 116 (C9ORF116) (N-Term) antibody
C9ORF116 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 9 Open Reading Frame 116 (C9ORF116) (AA 39-88) antibodyC9ORF116 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chromosome 9 Open Reading Frame 116 (C9ORF116) (N-Term) antibodyC9ORF116 适用: 人, 小鼠 WB, EIA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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PIERCE1 antibody can be used for detection of PIERCE1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PIERCE1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PIERCE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- C9ORF116 (Chromosome 9 Open Reading Frame 116 (C9ORF116))
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别名
- PIERCE1
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背景
- PIERCE1 Antibody: PIERCE1, also known as C9orf116, is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.
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基因ID
- 138162
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UniProt
- Q5BN46
抗原
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