CASKIN2 抗体 (N-Term)
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Quick Overview for CASKIN2 抗体 (N-Term) (ABIN6991638)
抗原
See all CASKIN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 380-430, N-Term
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特异性
- CASKIN2 antibody is predicted to not cross-react with other CASKIN family members. Three isoforms of CASKIN2 are known to exist, this antibody will not detect the shortest isoform.
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纯化方法
- CASKIN2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CASKIN2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human CASKIN2. The immunogen is located within amino acids 380 - 430 of CASKIN2.
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亚型
- IgG
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应用备注
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CASKIN2 antibody can be used for detection of EPAC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CASKIN2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CASKIN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CASKIN2 (CASK Interacting Protein 2 (CASKIN2))
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别名
- CASKIN2
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背景
- CASKIN2 Antibody: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting protein ) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN2 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. It is expressed ubiquitously with highest levels present in fetal and adult liver tissue.
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分子量
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Predicted: 123, 132 kDa
Observed: 120 kDa -
基因ID
- 57513
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NCBI登录号
- NP_065804
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UniProt
- Q8WXE0
抗原
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