TRIM21 抗体 (AA 290-340)
-
- 抗原 See all TRIM21 抗体
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
-
抗原表位
- AA 290-340
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This TRIM21 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- TRIM21 antibody is human specific. This antibody is predicted to not cross-react with TRIM6.
- 纯化方法
- TRIM21 antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-TRIM21 antibody was raised against a peptide corresponding to 16 amino acids near the center of human TRIM21. The immunogen is located within amino acids 290-340 of TRIM21.
- 亚型
- IgG
- Top Product
- Discover our top product TRIM21 Primary Antibody
-
anti-Tripartite Motif Containing 21 (TRIM21) (AA 80-330) antibody
TRIM21 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) (C-Term) antibodyVerified TRIM21 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) antibodyTRIM21 适用: 人 WB, IP, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) (AA 301-400) antibodyTRIM21 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) (AA 268-465) antibodyTRIM21 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) (AA 1-475) antibodyTRIM21 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) (AA 1-475) antibodyTRIM21 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) (C-Term) antibodyTRIM21 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) (AA 1-475) antibodyTRIM21 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 21 (TRIM21) (AA 68-175) antibodyTRIM21 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
-
WB: 0.5-2 μ,g/mL, IHC: 5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TRIM21 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- TRIM21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
- 抗原
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
- 别名
- TRIM21 (TRIM21 产品)
- 别名
- RNF81 antibody, RO52 antibody, SSA antibody, SSA1 antibody, Ro52 antibody, Ssa1 antibody, tripartite motif containing 21 antibody, tripartite motif-containing 21 antibody, TRIM21 antibody, Trim21 antibody
- 背景
- TRIM21, a member of the tripartite motif (TRIM) family, is a part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus (1). RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus (2). TRIM21 also acts as a cytosolic antibody receptor, detection of intracellular antibodies activate immune signaling by stimulating the transcription factor pathways of NF-kappaB, AP-1, IRF3, IRF5, and IRF7, resulting in the production of proinflammatory cytokines and the induction of an antiviral state (3).
- 分子量
-
Predicted: 54kD
Observed: 54 kD kDa - 基因ID
- 6737
- NCBI登录号
- NP_003132
- UniProt
- P19474
-
