PTCHD2 抗体 (AA 780-830)
This anti-PTCHD2 antibody is a 兔 多克隆 antibody detecting PTCHD2 in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for PTCHD2 抗体 (AA 780-830) (ABIN6991628)
抗原
See all PTCHD2 抗体
PTCHD2
(Patched Domain Containing 2 (PTCHD2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This PTCHD2 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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抗原表位
- AA 780-830
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特异性
- At least two isoforms of PTCHD2 are known to exist. This antibody is specific for PTCHD2 and will not recognize the other DISP family of proteins.
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纯化方法
- PTCHD2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PTCHD2 antibody was raised against a 19 amino acid synthetic peptide from near the center of human PTCHD2. The immunogen is located within amino acids 780 - 830 of PTCHD2.
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亚型
- IgG
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应用备注
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PTCHD2 antibody can be used for detection of EPAC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PTCHD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PTCHD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PTCHD2 (Patched Domain Containing 2 (PTCHD2))
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别名
- PTCHD2
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背景
- PTCHD2 Antibody: PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.
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基因ID
- 57540
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UniProt
- Q9P2K9
抗原
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