SIVA1 抗体 (N-Term)
Quick Overview for SIVA1 抗体 (N-Term) (ABIN6991621)
抗原
See all SIVA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- SIVA Antibody is affinity chromatography purified via peptide column.
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免疫原
- SIVA antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SIVA. The immunogen is located within the first 50 amino acids of SIVA.
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亚型
- IgY
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anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-175) antibody
SIVA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (Internal Region) antibodySIVA1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-175) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) antibodySIVA1 适用: 人 WB 宿主: 小鼠 Monoclonal 1C9 unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (AA 1-110) antibodySIVA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SIVA1, Apoptosis-Inducing Factor (SIVA1) (N-Term) antibodySIVA1 适用: 人, 小鼠 WB, IF, EIA 宿主: 小鸡 Polyclonal unconjugated
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应用备注
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SIVA antibody can be used for detection of EPAC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SIVA Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SIVA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
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别名
- SIVA
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背景
- SIVA Antibody: SIVA plays an important role in the apoptotic pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. SIVA is a small cysteine-rich protein with a unique N-terminal amphipathic helical region, a death domain homology region (DDHR) and a C-terminal cysteine-rich B-box-like or zinc-finger-like structure. The DDHR domain binds to CD27 and induces apoptosis in T cells through a caspase-dependent mitochondrial pathway. SIVA inhibits BCL2L1 isoform Bcl-xL anti-apoptotic activity and inhibits activation of NFκ,-B and promotes T-cell receptor-mediated apoptosis. SIVA represents a potential therapeutic target for the treatment of neuronal cell death diseases.
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基因ID
- 10572
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NCBI登录号
- NP_068355
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UniProt
- O15304
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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