PIWIL2 抗体 (AA 410-460)
Quick Overview for PIWIL2 抗体 (AA 410-460) (ABIN6991609)
抗原
See all PIWIL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 410-460
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特异性
- At least three isoforms of PIWI-L2 are known to exist, this antibody will only detect the two longest isoforms. PIWI-L2 antibody is predicted to not cross-react with other PIWI protein family members.
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纯化方法
- PIWI-L2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PIWI-L2 antibody was raised against a 17 amino acid synthetic peptide near the center of human PIWI-L2. The immunogen is located within amino acids 410 - 460 of PIWI-L2.
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亚型
- IgG
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anti-Piwi-Like 2 (PIWIL2) (C-Term) antibody
PIWIL2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 2 (PIWIL2) (AA 30-80) antibodyPIWIL2 适用: 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 2 (PIWIL2) antibodyPIWIL2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 2 (PIWIL2) (AA 1-973) antibodyPIWIL2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Piwi-Like 2 (PIWIL2) (AA 287-336) antibodyPIWIL2 适用: 人, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 2 (PIWIL2) (AA 90-119), (N-Term) antibodyPIWIL2 适用: 人 WB 宿主: 兔 Polyclonal RB39798 unconjugated
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应用备注
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PIWI-L2 antibody can be used for detection of PIWI-L2 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PIWI-L2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PIWI-L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PIWIL2 (Piwi-Like 2 (PIWIL2))
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别名
- PIWI-L2
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背景
- PIWI-L2 Antibody: PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers. In these tumors, PIWI-L2 silences the expression of STAT3, a regulator of Bcl-XL and cyclin D1, allowing the proliferation and survival of breast cancer stem cells. Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other cancers.
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基因ID
- 55124
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NCBI登录号
- NP_00129193
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UniProt
- Q8TC59
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途径
- Stem Cell Maintenance
抗原
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