PRICKLE2 抗体 (AA 420-470)
Quick Overview for PRICKLE2 抗体 (AA 420-470) (ABIN6991607)
抗原
See all PRICKLE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 420-470
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特异性
- Two isoforms of PRICKLE2 are known to exist. PRICKLE2 antibody is predicted to not cross-react with other PRICKLE protein family members.
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纯化方法
- PRICKLE2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PRICKLE2 antibody was raised against a 15 amino acid synthetic peptide near the center of human PRICKLE2. The immunogen is located within amino acids 420 - 470 of PRICKLE2.
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亚型
- IgG
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anti-Prickle Homolog 2 (PRICKLE2) (AA 615-844) antibody
PRICKLE2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prickle Homolog 2 (PRICKLE2) (AA 615-844) antibodyPRICKLE2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Prickle Homolog 2 (PRICKLE2) (Internal Region) antibodyPRICKLE2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prickle Homolog 2 (PRICKLE2) (C-Term) antibodyPRICKLE2 适用: 人, 小鼠, 大鼠, Bat, 小鸡, Cow, 犬, 豚鼠, 马, 猴, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Prickle Homolog 2 (PRICKLE2) (Middle Region) antibodyPRICKLE2 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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PRICKLE2 antibody can be used for detection of PRICKLE2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PRICKLE2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PRICKLE2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PRICKLE2 (Prickle Homolog 2 (PRICKLE2))
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别名
- PRICKLE2
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背景
- PRICKLE2 Antibody: PRICKLE2, also known as Pk2 or EPM5, is a member of a highly conserved protein family that function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity. Both PRICKLE2 and the related protein PRICKLE1 are expressed in postmitotic neurons and promote neurite outgrowth, and both proteins promote neurite outgrowth via the Dishevelled dependent pathway in C1300 cells. PRICKLE2 localizes to the postsynaptic density and interacts with PSD-95 and NMDA receptors. Defects in the gene encoding PRICKLE2 are associated with autosomal recessive progressive myoclonic epilepsy.
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基因ID
- 166336
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NCBI登录号
- NP_942559
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UniProt
- Q7Z3G6
抗原
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