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AFAP 抗体 (N-Term)

AFAP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991604
发货至: 中国
  • 抗原 See all AFAP (AFAP1) 抗体
    AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-80, N-Term
    适用
    • 44
    • 22
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 40
    • 4
    • 1
    克隆类型
    • 42
    • 3
    多克隆
    标记
    • 21
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AFAP antibody is un-conjugated
    应用范围
    • 42
    • 17
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    特异性
    Monomer and homomultimer of AFAP1 are known to exist, AFAP1 antibody is predicted to not cross-react with other AFAP family members.
    纯化方法
    AFAP1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    AFAP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human AFAP1. The immunogen is located within amino acids 30 - 80 of AFAP1.
    亚型
    IgG
    Top Product
    Discover our top product AFAP1 Primary Antibody
  • 应用备注
    AFAP1 antibody can be used for detection of AFAP1 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    AFAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    AFAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
    别名
    AFAP1 (AFAP1 产品)
    别名
    afap antibody, afap-110 antibody, AFAP antibody, AFAP-110 antibody, AFAP110 antibody, 2600003E23Rik antibody, 9630044L16Rik antibody, AI848729 antibody, Afap antibody, mKIAA3018 antibody, actin filament associated protein 1 antibody, AFAP1 antibody, afap1 antibody, Afap1 antibody
    背景
    AFAP1 Antibody: The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP1 has a fundamental role in actin cytoskeleton arrangement. It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains, including 2 pleckstrin homology (PH) domains, a Src homology 3-binding (SH3-binding) motif, and several SH2-binding motifs. It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells. AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis.
    基因ID
    60312
    NCBI登录号
    NP_940997
    UniProt
    Q8N556
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