AFAP 抗体 (N-Term)
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北京 101111
Quick Overview for AFAP 抗体 (N-Term) (ABIN6991604)
抗原
See all AFAP (AFAP1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-80, N-Term
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特异性
- Monomer and homomultimer of AFAP1 are known to exist, AFAP1 antibody is predicted to not cross-react with other AFAP family members.
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纯化方法
- AFAP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- AFAP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human AFAP1. The immunogen is located within amino acids 30 - 80 of AFAP1.
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亚型
- IgG
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anti-Actin Filament Associated Protein 1 (AFAP1) (AA 352-572) antibody
AFAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1 (AFAP1) (AA 461-730) antibodyAFAP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1 (AFAP1) (AA 286-325) antibodyAFAP1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1 (AFAP1) (AA 461-730) antibodyAFAP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1 (AFAP1) (N-Term) antibodyAFAP1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1 (AFAP1) (AA 1-730) antibodyAFAP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1 (AFAP1) (AA 301-350) antibodyAFAP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Actin Filament Associated Protein 1 (AFAP1) (Middle Region) antibodyAFAP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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AFAP1 antibody can be used for detection of AFAP1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- AFAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- AFAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- AFAP (AFAP1) (Actin Filament Associated Protein 1 (AFAP1))
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别名
- AFAP1
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背景
- AFAP1 Antibody: The actin filament-associated protein AFAP1 (AFAP-110) is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP1 has a fundamental role in actin cytoskeleton arrangement. It contains a carboxyterminal actin-binding domain that directly binds to F-actin and serves as an adaptor protein in the regulation of SRC and PKC signal transduction by several functional domains, including 2 pleckstrin homology (PH) domains, a Src homology 3-binding (SH3-binding) motif, and several SH2-binding motifs. It is overexpressed in prostate carcinoma and contributes to tumor growth by regulating cell-matrix adhesions and migration in the cancer cells. AFAP1 represent a possible therapeutic target for controlling tumorigenesis and metastasis.
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基因ID
- 60312
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NCBI登录号
- NP_940997
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UniProt
- Q8N556
抗原
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