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DRAXIN 抗体 (C-Term)

DRAXIN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991584
发货至: 中国
  • 抗原 See all DRAXIN 抗体
    DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    C-Term
    适用
    • 37
    • 21
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    • 4
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    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 36
    • 3
    克隆类型
    • 39
    多克隆
    标记
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
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    This DRAXIN antibody is un-conjugated
    应用范围
    • 39
    • 26
    • 13
    • 8
    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    At least three isoforms of Neucrin are known to exist, this antibody will detect the two shorter isoforms. Neucrin antibody is predicted to not cross-react with RILP.
    纯化方法
    NEUCRIN Antibody is affinity chromatography purified via peptide column.
    免疫原
    Neucrin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human Neucrin. The immunogen is located within the last 50 amino acids of NEUCRIN.
    亚型
    IgG
    Top Product
    Discover our top product DRAXIN Primary Antibody
  • 应用备注
    Neucrin antibody can be used for detection of Neucrin by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    NEUCRIN Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    NEUCRIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
    别名
    NEUCRIN (DRAXIN 产品)
    别名
    C1orf187 antibody, draxin antibody, AGPA3119 antibody, UNQ3119 antibody, neucrin antibody, 2610109H07Rik antibody, MGC113312 antibody, dorsal inhibitory axon guidance protein antibody, DRAXIN antibody, Draxin antibody, draxin antibody
    背景
    NEUCRIN Antibody: Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures. It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin. Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures. Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.
    基因ID
    374946
    UniProt
    Q8NBI3
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