NETO1 抗体 (C-Term)
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Quick Overview for NETO1 抗体 (C-Term) (ABIN6991577)
抗原
See all NETO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-400, C-Term
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特异性
- NETO1 antibody is predicted to not cross-react with other NETO protein family members.
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纯化方法
- NETO1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- NETO1 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human NETO1. The immunogen is located within amino acids 350 - 400 of NETO1.
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亚型
- IgG
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应用备注
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NETO1 antibody can be used for detection of NETO1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NETO1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NETO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NETO1 (Neuropilin (NRP) and Tolloid (TLL)-Like 1 (NETO1))
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别名
- NETO1
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背景
- NETO1 Antibody: Neuropilin and tolloid-like protein 1 (NETO1) is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory.
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分子量
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Predicted: 60 kDa
Observed: 60 kDa -
基因ID
- 81832
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NCBI登录号
- NP_694821
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UniProt
- Q8TDF5
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途径
- Regulation of long-term Neuronal Synaptic Plasticity
抗原
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