UHRF1BP1 抗体 (AA 890-940)
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Quick Overview for UHRF1BP1 抗体 (AA 890-940) (ABIN6991574)
抗原
See all UHRF1BP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 890-940
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特异性
- UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L
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纯化方法
- UHRF1BP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- UHRF1BP1 antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1. The immunogen is located within amino acids 890 - 940 of UHRF1BP1.
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亚型
- IgG
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应用备注
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UHRF1BP1 antibody can be used for detection of UHRF1BP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- UHRF1BP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- UHRF1BP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))
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别名
- UHRF1BP1
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背景
- UHRF1BP1 Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.
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基因ID
- 54887
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NCBI登录号
- NP_060224
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UniProt
- Q6BDS2
抗原
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