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TMEM59L 抗体 (C-Term)

TMEM59L 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991563
发货至: 中国
  • 抗原 See all TMEM59L 抗体
    TMEM59L (Transmembrane Protein 59-Like (TMEM59L))
    抗原表位
    • 15
    • 5
    • 1
    • 1
    • 1
    AA 220-270, C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMEM59L antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    Multiple isoforms of TMEM59L are known to exist. TMEM59L antibody is predicted to not cross-react TMEM59.
    纯化方法
    TMEM59L Antibody is affinity chromatography purified via peptide column.
    免疫原
    TMEM59L antibody was raised against a 19 amino acid synthetic peptide near carboxy terminus of human TMEM59L. The immunogen is located within amino acids 220 - 270 of TMEM59L.
    亚型
    IgG
    Top Product
    Discover our top product TMEM59L Primary Antibody
  • 应用备注
    TMEM59L antibody can be used for detection of TMEM59L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TMEM59L Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TMEM59L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TMEM59L (Transmembrane Protein 59-Like (TMEM59L))
    别名
    TMEM59L (TMEM59L 产品)
    别名
    LOC719572 antibody, BSMAP antibody, C19orf4 antibody, 5330410G16Rik antibody, RGD1305557 antibody, transmembrane protein 59 like antibody, transmembrane protein 59-like antibody, TMEM59L antibody, Tmem59l antibody
    背景
    TMEM59L Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
    基因ID
    25789
    NCBI登录号
    NP_036241
    UniProt
    Q9UK28
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