TMEM59L 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for TMEM59L 抗体 (C-Term) (ABIN6991563)
抗原
See all TMEM59L 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 220-270, C-Term
-
特异性
- Multiple isoforms of TMEM59L are known to exist. TMEM59L antibody is predicted to not cross-react TMEM59.
-
纯化方法
- TMEM59L Antibody is affinity chromatography purified via peptide column.
-
免疫原
- TMEM59L antibody was raised against a 19 amino acid synthetic peptide near carboxy terminus of human TMEM59L. The immunogen is located within amino acids 220 - 270 of TMEM59L.
-
亚型
- IgG
-
-
anti-Transmembrane Protein 59-Like (TMEM59L) (AA 27-267) antibody
TMEM59L 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59-Like (TMEM59L) (AA 21-70) antibodyTMEM59L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59-Like (TMEM59L) (N-Term) antibodyTMEM59L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59-Like (TMEM59L) (C-Term) antibodyTMEM59L 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
TMEM59L antibody can be used for detection of TMEM59L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- TMEM59L Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- TMEM59L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- TMEM59L (Transmembrane Protein 59-Like (TMEM59L))
-
别名
- TMEM59L
-
背景
- TMEM59L Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
-
基因ID
- 25789
-
NCBI登录号
- NP_036241
-
UniProt
- Q9UK28
抗原
-
