TMEM59L 抗体 (C-Term)
Quick Overview for TMEM59L 抗体 (C-Term) (ABIN6991563)
抗原
See all TMEM59L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-270, C-Term
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特异性
- Multiple isoforms of TMEM59L are known to exist. TMEM59L antibody is predicted to not cross-react TMEM59.
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纯化方法
- TMEM59L Antibody is affinity chromatography purified via peptide column.
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免疫原
- TMEM59L antibody was raised against a 19 amino acid synthetic peptide near carboxy terminus of human TMEM59L. The immunogen is located within amino acids 220 - 270 of TMEM59L.
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亚型
- IgG
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anti-Transmembrane Protein 59-Like (TMEM59L) (AA 27-267) antibody
TMEM59L 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59-Like (TMEM59L) (AA 21-70) antibodyTMEM59L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59-Like (TMEM59L) (N-Term) antibodyTMEM59L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59-Like (TMEM59L) (C-Term) antibodyTMEM59L 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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TMEM59L antibody can be used for detection of TMEM59L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TMEM59L Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TMEM59L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TMEM59L (Transmembrane Protein 59-Like (TMEM59L))
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别名
- TMEM59L
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背景
- TMEM59L Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
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基因ID
- 25789
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NCBI登录号
- NP_036241
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UniProt
- Q9UK28
抗原
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