CCDC141 抗体 (N-Term)
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北京 101111
Quick Overview for CCDC141 抗体 (N-Term) (ABIN6991553)
抗原
See all CCDC141 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90, N-Term
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特异性
- At least four isoforms of CCDC141 are known to exist.
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纯化方法
- CCDC141 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CCDC141 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CCDC141. The immunogen is located within amino acids 40 - 90 of CCDC141.
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 141 (CCDC141) (AA 639-688) antibody
CCDC141 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 141 (CCDC141) (Middle Region) antibodyCCDC141 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 141 (CCDC141) (AA 1-30), (N-Term) antibodyCCDC141 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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CCDC141 antibody can be used for detection of CCDC141 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CCDC141 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CCDC141 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))
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别名
- CCDC141
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背景
- CCDC141 Antibody: Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.
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基因ID
- 285025
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NCBI登录号
- NP_775919
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UniProt
- Q6ZP82
抗原
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