TMEM88 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for TMEM88 抗体 (C-Term) (ABIN6991552)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 110-160, C-Term
-
特异性
- At least two isoforms of TMEM88 are known to exist, this antibody will recognize both isoforms.
-
纯化方法
- TMEM88 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- TMEM88 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TMEM88. The immunogen is located within amino acids 110 - 160 of TMEM88.
-
亚型
- IgG
-
-
-
-
应用备注
-
TMEM88 antibody can be used for detection of TMEM88 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- TMEM88 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- TMEM88 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- TMEM88 (Transmembrane Protein 88 (TMEM88))
-
别名
- TMEM88
-
背景
- TMEM88 Antibody: Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.
-
基因ID
- 92162
-
UniProt
- Q6PEY1
抗原
-