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TRMT12 抗体 (N-Term)

TRMT12 适用: 人, 小鼠 ELISA, WB, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991541
发货至: 中国
  • 抗原 See all TRMT12 抗体
    TRMT12 (tRNA Methyltransferase 12 Homolog (TRMT12))
    抗原表位
    • 2
    • 1
    N-Term
    适用
    • 11
    • 8
    • 1
    人, 小鼠
    宿主
    • 10
    • 1
    克隆类型
    • 11
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRMT12 antibody is un-conjugated
    应用范围
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
    特异性
    TYW2 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW2 are known to exist, this antibody will detect both isoforms
    纯化方法
    TYW2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    TYW2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TYW2. The immunogen is located within the first 50 amino acids of TYW2.
    亚型
    IgG
    Top Product
    Discover our top product TRMT12 Primary Antibody
  • 应用备注
    TYW2 antibody can be used for detection of TYW2 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TYW2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    TYW2 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TRMT12 (tRNA Methyltransferase 12 Homolog (TRMT12))
    别名
    TYW2 (TRMT12 产品)
    别名
    4632406N01Rik antibody, AI449275 antibody, Tyw2 antibody, TRM12 antibody, TYW2 antibody, RGD1307127 antibody, trmt12 antibody, tRNA methyltranferase 12 antibody, tRNA methyltransferase 12 homolog antibody, tRNA methyltransferase 12 antibody, tRNA methyltransferase 12 homolog (S. cerevisiae) antibody, Trmt12 antibody, TRMT12 antibody, trmt12 antibody
    背景
    TYW2 Antibody: TYW2, also known as TRM12, is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW2 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. TYW2 was found to be amplified in 7 of 8 breast cancers cell lines analyzed, and qPCR analysis of 30 breast tumors showed overexpression of TYW2 mRNA of over 2-fold in 26, suggesting that TYW2 may play a role in breast cancer.
    基因ID
    55039
    UniProt
    Q53H54
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