TRMT12 抗体 (N-Term)
This anti-TRMT12 antibody is a 兔 多克隆 antibody detecting TRMT12 in ELISA, WB 和 ICC. Suitable for 人 和 小鼠.
Quick Overview for TRMT12 抗体 (N-Term) (ABIN6991541)
抗原
See all TRMT12 抗体
TRMT12
(tRNA Methyltransferase 12 Homolog (TRMT12))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This TRMT12 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
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抗原表位
- N-Term
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特异性
- TYW2 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW2 are known to exist, this antibody will detect both isoforms
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纯化方法
- TYW2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TYW2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TYW2. The immunogen is located within the first 50 amino acids of TYW2.
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亚型
- IgG
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anti-tRNA Methyltransferase 12 Homolog (TRMT12) antibody
TRMT12 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Methyltransferase 12 Homolog (TRMT12) (AA 1-448) antibodyTRMT12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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TYW2 antibody can be used for detection of TYW2 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TYW2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- TYW2 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TRMT12 (tRNA Methyltransferase 12 Homolog (TRMT12))
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别名
- TYW2
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背景
- TYW2 Antibody: TYW2, also known as TRM12, is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW2 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. TYW2 was found to be amplified in 7 of 8 breast cancers cell lines analyzed, and qPCR analysis of 30 breast tumors showed overexpression of TYW2 mRNA of over 2-fold in 26, suggesting that TYW2 may play a role in breast cancer.
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基因ID
- 55039
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UniProt
- Q53H54
抗原
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