TYW1 抗体 (C-Term)
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北京 101111
Quick Overview for TYW1 抗体 (C-Term) (ABIN6991540)
抗原
See all TYW1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 520-570, C-Term
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特异性
- TYW1 antibody is predicted to not cross-react with other TYW protein family members. At least three isoforms of TYW1 are known to exist, this antibody will only detect the two larger isoforms.
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纯化方法
- TYW1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TYW1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human TYW1. The immunogen is located within amino acids 520 - 570 of TYW1.
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亚型
- IgG
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anti-tRNA-YW Synthesizing Protein 1 Homolog (TYW1) (AA 1-384) antibody
TYW1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-tRNA-YW Synthesizing Protein 1 Homolog (TYW1) (AA 1-384) antibodyTYW1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G5 unconjugated
anti-tRNA-YW Synthesizing Protein 1 Homolog (TYW1) (C-Term) antibodyTYW1 适用: 人, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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TYW1 antibody can be used for detection of TYW1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TYW1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- TYW1 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TYW1 (tRNA-YW Synthesizing Protein 1 Homolog (TYW1))
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别名
- TYW1
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背景
- TYW1 Antibody: TYW1, also known as TYW1A, RSAFD1 or YPL207W, is a 732 amino acid protein containing one flavodoxin-like domain that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW1 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. TYW1 binds to one 4Fe-4S cluster and is located on human chromosome 7. Defects in some of the genes on chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome, suggesting that TYW1 may play a role in these conditions
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基因ID
- 55253
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NCBI登录号
- NP_060734
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UniProt
- Q9NV66
抗原
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