Anosmin 抗体 (AA 430-480)
This anti-Anosmin antibody is a 兔 多克隆 antibody detecting Anosmin in WB, ELISA, ICC 和 IF. Suitable for 人.
Quick Overview for Anosmin 抗体 (AA 430-480) (ABIN6991537)
抗原
See all Anosmin (ANOS1) 抗体
Anosmin (ANOS1)
适用
人
宿主
兔
克隆类型
多克隆
标记
This Anosmin antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
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抗原表位
- AA 430-480
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纯化方法
- Anosmin Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anosmin antibody was raised against an 18 amino acid synthetic peptide near the center of human Anosmin. The immunogen is located within amino acids 430 - 480 of Anosmin.
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亚型
- IgG
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anti-Anosmin (ANOS1) (Internal Region) antibody
ANOS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Anosmin antibody can be used for detection of Anosmin by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Anosmin Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Anosmin antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Anosmin (ANOS1)
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别名
- Anosmin
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背景
- Anosmin Antibody: Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
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基因ID
- 3730
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NCBI登录号
- NP_000207
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UniProt
- P23352
抗原
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