MSI2 抗体 (N-Term)
Quick Overview for MSI2 抗体 (N-Term) (ABIN6991532)
抗原
See all MSI2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-80, N-Term
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特异性
- MSI2 antibody is predicted to not cross-react with MSI1. Multiple isoforms of MSI2 are known to exist.
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纯化方法
- MSI2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- MSI2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MSI2. The immunogen is located within amino acids 30 - 80 of MSI2.
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亚型
- IgG
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anti-Musashi Homolog 2 (MSI2) antibody
MSI2 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F10 unconjugated
anti-Musashi Homolog 2 (MSI2) (N-Term) antibodyMSI2 适用: 人, 小鼠, 大鼠, 斑马鱼, 兔, Cow, 马, Pig, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 1-328) antibodyMSI2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 1-328) antibodyMSI2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-Musashi Homolog 2 (MSI2) antibodyMSI2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 1-328) antibodyMSI2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 37-86) antibodyMSI2 适用: 人, 小鼠, 大鼠, 斑马鱼, 兔, Cow, 马, 非洲爪蟾, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 33-43) antibodyVerified MSI2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (N-Term) antibodyVerified MSI2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 1-190) antibodyMSI2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4A6D10 unconjugated
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应用备注
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MSI2 antibody can be used for detection of MSI2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL and immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MSI2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- MSI2 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MSI2 (Musashi Homolog 2 (MSI2))
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别名
- MSI2
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背景
- MSI2 Antibody: Musashi2 (MSI2) is an RNA-binding protein that is highly expressed in precursor cells in the ventricular and subventricular zones of the developing mammalian CNS. Like the related MSI1, MSI2 has been suggested to be involved stem cell production and maintenance. MSI2 is the predominant MSI protein in hematopoietic stem cells, and its knockdown leads to reduced engraftment and depletion in vivo. Expression levels of MSI2 are elevated in myeloid leukemia cells lines, and MSI2 appears to cooperate with BCR-ABL1 to induce an aggressive leukemia, the level of MSI2 directly correlates with decreased survival in patients. MSI2 negatively regulates the asymmetric cell fate determinant NUMB, suggesting that this signaling pathway may provide future targets for future therapies.
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基因ID
- 124540
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UniProt
- Q96DH6
抗原
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