PRR5L 抗体 (AA 220-270)
This anti-PRR5L antibody is a 兔 多克隆 antibody detecting PRR5L in WB, ELISA, IF 和 ICC. Suitable for 人 和 小鼠.
Quick Overview for PRR5L 抗体 (AA 220-270) (ABIN6991524)
抗原
See all PRR5L 抗体
PRR5L
(Proline Rich 5 Like (PRR5L))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This PRR5L antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
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抗原表位
- AA 220-270
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特异性
- At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.
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纯化方法
- PRR5L Antibody is affinity chromatography purified via peptide column.
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免疫原
- PRR5L antibody was raised against a 17 amino acid synthetic peptide near the center of human PRR5L. The immunogen is located within amino acids 220 - 270 of PRR5L.
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亚型
- IgG
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anti-Proline Rich 5 Like (PRR5L) (Center) antibody
PRR5L 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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PRR5L antibody can be used for detection of PRR5L by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PRR5L Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PRR5L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PRR5L (Proline Rich 5 Like (PRR5L))
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别名
- PRR5L
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背景
- PRR5L Antibody: Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.
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基因ID
- 79899
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NCBI登录号
- NP_001153639
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UniProt
- Q6MZQ0
抗原
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