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PRR5L 抗体 (AA 220-270)

The 兔 多克隆 anti-PRR5L antibody (ABIN6991524) specifically detects PRR5L in WB, ELISA, IF 和 ICC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6991524
发货至: 中国
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Quick Overview for PRR5L 抗体 (AA 220-270) (ABIN6991524)

抗原

See all PRR5L 抗体
PRR5L (Proline Rich 5 Like (PRR5L))

适用

人, 小鼠

宿主

  • 3

克隆类型

  • 3
多克隆

标记

  • 3
This PRR5L antibody is un-conjugated

应用范围

  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 1
    • 1
    AA 220-270

    特异性

    At least three isoforms of PRR5L are known to exist, this antibody will recognize only isoforms a and b. PRR5L antibody will not cross-react with PPR5.

    纯化方法

    PRR5L Antibody is affinity chromatography purified via peptide column.

    免疫原

    PRR5L antibody was raised against a 17 amino acid synthetic peptide near the center of human PRR5L. The immunogen is located within amino acids 220 - 270 of PRR5L.

    亚型

    IgG
  • 应用备注

    PRR5L antibody can be used for detection of PRR5L by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PRR5L Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    PRR5L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    PRR5L (Proline Rich 5 Like (PRR5L))

    别名

    PRR5L

    背景

    PRR5L Antibody: Proline-rich protein 5-like (PRR5L), also known as Protor-2, is structurally similar to PRR5 and also binds to the mTOR complex 2 (mTORC2). PRR5L is not required for mTORC2 integrity or kinase activity, but dissociates from mTORC2 upon knockdown of tuberous sclerosis complex 1 (TSC1) and TSC2. Knockdown of PRR5L reduced apoptosis in mTORC2 deficient cells as well as cells where mTOR was active, suggesting that mTORC2-dissociated PRR5L may promote apoptosis, and thus play a role in the balance between cell growth and cell death.

    基因ID

    79899

    NCBI登录号

    NP_001153639

    UniProt

    Q6MZQ0
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