Two isoforms of SLAMF2 are known to exist, this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.
纯化方法
SLAMF2 Antibody is affinity chromatography purified via peptide column.
免疫原
SLAMF2 antibody was raised against a 19 amino acid synthetic peptide near the center of human SLAMF2. The immunogen is located within amino acids 90 - 140 of SLAMF2.
SLAMF2 antibody can be used for detection of SLAMF2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
SLAMF2 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
SLAMF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
SLAMF2 Antibody: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.