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LIF 抗体 (AA 50-100)

LIF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991509
发货至: 中国
  • 抗原 See all LIF 抗体
    LIF (Leukemia Inhibitory Factor (LIF))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-100
    适用
    • 45
    • 15
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    • 8
    • 2
    • 2
    • 2
    • 1
    克隆类型
    • 51
    • 6
    多克隆
    标记
    • 39
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIF antibody is un-conjugated
    应用范围
    • 46
    • 25
    • 24
    • 14
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    特异性
    At least two isoforms of LIF are known to exist.
    纯化方法
    LIF Antibody is affinity chromatography purified via peptide column.
    免疫原
    Anti-LIF antibody was raised against a peptide corresponding to 16 amino acids near the center of human LIF. The immunogen is located within amino acids 50-100 of LIF.
    亚型
    IgG
    Top Product
    Discover our top product LIF Primary Antibody
  • 应用备注
    WB: 1-4 μ,g/mL, IF: 20 μ,g/mL.

    Antibody validated: Western Blot in human, mouse and rat samples, Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    LIF Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    LIF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    LIF (Leukemia Inhibitory Factor (LIF))
    别名
    LIF (LIF 产品)
    别名
    CDF antibody, DIA antibody, HILDA antibody, MLPLI antibody, LIF, interleukin 6 family cytokine antibody, leukemia inhibitory factor antibody, LIF antibody, Lif antibody
    背景
    LIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.
    分子量
    Predicted: 22kD

    Observed: 26kD (Post-modifications: N-linked Glycosylations) kDa
    基因ID
    3976
    NCBI登录号
    NP_002300
    UniProt
    P15018
    途径
    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
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