LIF 抗体 (AA 50-100)
Quick Overview for LIF 抗体 (AA 50-100) (ABIN6991509)
抗原
See all LIF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100
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特异性
- At least two isoforms of LIF are known to exist.
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纯化方法
- LIF Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-LIF antibody was raised against a peptide corresponding to 16 amino acids near the center of human LIF. The immunogen is located within amino acids 50-100 of LIF.
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亚型
- IgG
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anti-Leukemia Inhibitory Factor (LIF) (AA 2-201) antibody
LIF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leukemia Inhibitory Factor (LIF) (AA 2-201) antibodyLIF 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Leukemia Inhibitory Factor (LIF) (AA 72-101) antibodyLIF 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Leukemia Inhibitory Factor (LIF) (AA 101-202) antibodyLIF 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leukemia Inhibitory Factor (LIF) (AA 23-202) antibodyLIF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leukemia Inhibitory Factor (LIF) (AA 72-101) antibodyLIF 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21725 unconjugated
anti-Leukemia Inhibitory Factor (LIF) (C-Term) antibodyLIF 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leukemia Inhibitory Factor (LIF) (AA 23-202) antibodyLIF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Leukemia Inhibitory Factor (LIF) (C-Term) antibodyLIF 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leukemia Inhibitory Factor (LIF) (AA 25-203) antibodyLIF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1-4 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LIF Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- LIF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- LIF (Leukemia Inhibitory Factor (LIF))
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别名
- LIF
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背景
- LIF Antibody: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. LIF was initially recognized by its ability to induce terminal differentiation of myeloid leukemic cells. It is a member of the IL-6 cytokine superfamily and can be highly glycosylated. LIF signaling is transduced through the LIF-R/gp130 receptor complex, leading to the phosphorylation and activation of the JAK/STAT pathway. Recent evidence shows that LIF inhibits cardiomyogenesis in embryonic stem cells via STAT3 activation.
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分子量
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Predicted: 22kD
Observed: 26kD (Post-modifications: N-linked Glycosylations) kDa -
基因ID
- 3976
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NCBI登录号
- NP_002300
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UniProt
- P15018
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途径
- JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding
抗原
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