TM4SF1 抗体 (N-Term)
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北京 101111
Quick Overview for TM4SF1 抗体 (N-Term) (ABIN6991504)
抗原
See all TM4SF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- At least three isoforms of TM4SF1 are known to exist, this antibody will recognize only the two largest isoforms. TM4SF1 antibody is predicted to not cross-react with other tetraspanin proteins.
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纯化方法
- TM4SF1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TM4SF1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human TM4SF1. The immunogen is located within the first 50 amino acids of TM4SF1.
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亚型
- IgG
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anti-Transmembrane 4 L Six Family Member 1 (TM4SF1) (AA 115-161) antibody
TM4SF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane 4 L Six Family Member 1 (TM4SF1) (AA 16-45), (N-Term) antibodyTM4SF1 适用: 人, 小鼠 IHC (p), WB 宿主: 兔 Polyclonal RB32161 unconjugated
anti-Transmembrane 4 L Six Family Member 1 (TM4SF1) (AA 110-202) antibodyTM4SF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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TM4SF1 antibody can be used for detection of TM4SF1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TM4SF1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TM4SF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))
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别名
- TM4SF1
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背景
- TM4SF1 Antibody: TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.
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基因ID
- 4071
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NCBI登录号
- NP_055035
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UniProt
- P30408
抗原
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