RABGEF1 抗体 (AA 430-480)
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Quick Overview for RABGEF1 抗体 (AA 430-480) (ABIN6991502)
抗原
See all RABGEF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 430-480
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特异性
- At least four isoforms of RABEX5 are known to exist, this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.
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纯化方法
- RABEX5 Antibody is affinity chromatography purified via peptide column.
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免疫原
- RABEX5 antibody was raised against a 19 amino acid synthetic peptide near the center terminus of human RABEX5. The immunogen is located within amino acids 430 - 480 of RABEX5.
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亚型
- IgG
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anti-RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (AA 1-491) antibody
RABGEF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (AA 1-491) antibodyRABGEF1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (N-Term) antibodyRABGEF1 适用: 人, 小鼠, 大鼠, Cow, 犬, 小鸡, 山羊, 马, 斑马鱼, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (N-Term) antibodyRABGEF1 适用: 人, 小鼠, 大鼠, Cow, 犬, 山羊, 马, 斑马鱼, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (C-Term) antibodyRABGEF1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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RABEX5 antibody can be used for detection of RABEX5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RABEX5 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- RABEX5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
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别名
- RABEX5
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背景
- RABEX5 Antibody: RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.
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基因ID
- 27342
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NCBI登录号
- NP_055319
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UniProt
- Q9UJ41
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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