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MYZAP 抗体 (C-Term)

MYZAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991501
发货至: 中国
  • 抗原 See all MYZAP 抗体
    MYZAP (Myocardial Zonula Adherens Protein (MYZAP))
    抗原表位
    AA 400-450, C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 2
    • 1
    克隆类型
    • 2
    • 1
    多克隆
    标记
    • 3
    This MYZAP antibody is un-conjugated
    应用范围
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    Multiple isoforms of MYOZAP are known to exist.
    纯化方法
    MYOZAP Antibody is affinity chromatography purified via peptide column.
    免疫原
    MYOZAP antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human MYOZAP. The immunogen is located within amino acids 400 - 450 of MYOZAP.
    亚型
    IgG
  • 应用备注
    MYOZAP antibody can be used for detection of MYOZAP by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    MYOZAP Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    MYOZAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    MYZAP (Myocardial Zonula Adherens Protein (MYZAP))
    别名
    MYOZAP (MYZAP 产品)
    别名
    AA407270 antibody, AV006038 antibody, Gcom1 antibody, Gm640 antibody, Grinl1a7 antibody, Myozap antibody, Myzap antibody, GLURR2 antibody, GRINL1B antibody, GCOM1 antibody, Gup antibody, Gup1 antibody, Gup2 antibody, MYOZAP antibody, myocardial zonula adherens protein antibody, GRINL1B complex locus 2 (pseudogene) antibody, Myzap antibody, GCOM2 antibody, MYZAP antibody
    背景
    MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
    基因ID
    100820829
    NCBI登录号
    NP_001018110
    UniProt
    P0CAP1
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