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MYZAP 抗体 (C-Term)

This anti-MYZAP antibody is a 兔 多克隆 antibody detecting MYZAP in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991501
发货至: 中国

Quick Overview for MYZAP 抗体 (C-Term) (ABIN6991501)

抗原

See all MYZAP 抗体
MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

适用

人, 小鼠, 大鼠

宿主

  • 2
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克隆类型

  • 2
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多克隆

标记

  • 3
This MYZAP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    AA 400-450, C-Term

    特异性

    Multiple isoforms of MYOZAP are known to exist.

    纯化方法

    MYOZAP Antibody is affinity chromatography purified via peptide column.

    免疫原

    MYOZAP antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human MYOZAP. The immunogen is located within amino acids 400 - 450 of MYOZAP.

    亚型

    IgG
  • 应用备注

    MYOZAP antibody can be used for detection of MYOZAP by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    MYOZAP Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    MYOZAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    MYZAP (Myocardial Zonula Adherens Protein (MYZAP))

    别名

    MYOZAP

    背景

    MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.

    基因ID

    100820829

    NCBI登录号

    NP_001018110

    UniProt

    P0CAP1
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