N4BP1 抗体 (N-Term)
Quick Overview for N4BP1 抗体 (N-Term) (ABIN6991485)
抗原
See all N4BP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- At least three isoforms of N4BP1 are known to exist, this antibody will only detect the longest isoform.
-
纯化方法
- N4BP1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- N4BP1 antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human N4BP1. The immunogen is located within the first 50 amino acids of N4BP1.
-
亚型
- IgG
-
-
anti-NEDD4 Binding Protein 1 (N4BP1) (Internal Region) antibody
N4BP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NEDD4 Binding Protein 1 (N4BP1) (AA 190-590) antibodyN4BP1 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NEDD4 Binding Protein 1 (N4BP1) (AA 1-896) antibodyN4BP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NEDD4 Binding Protein 1 (N4BP1) (Internal Region) antibodyN4BP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NEDD4 Binding Protein 1 (N4BP1) (AA 383-432) antibodyN4BP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
N4BP1 antibody can be used for detection of N4BP1 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- N4BP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- N4BP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- N4BP1 (NEDD4 Binding Protein 1 (N4BP1))
-
别名
- N4BP1
-
背景
- N4BP1 Antibody: Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
-
基因ID
- 9683
-
NCBI登录号
- NP_694574
-
UniProt
- O75113
抗原
-
