LRRTM3 抗体 (C-Term)
LRRTM3
适用: 小鼠, 人, 大鼠
WB, ELISA, IF, IHC (p)
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all LRRTM3 抗体
- LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))
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抗原表位
- C-Term
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适用
- 小鼠, 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRRTM3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- At least two isoforms of LRRTM3 are known to exist, this antibody will only detect the larger isoform.
- 纯化方法
- LRRTM3 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- LRRTM3 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human LRRTM3. The immunogen is located within the last 50 amino acids of LRRTM3.
- 亚型
- IgG
- Top Product
- Discover our top product LRRTM3 Primary Antibody
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- 应用备注
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LRRTM3 antibody can be used for detection of LRRTM3 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- LRRTM3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- LRRTM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))
- 别名
- LRRTM3 (LRRTM3 产品)
- 别名
- 9630044H04Rik antibody, leucine rich repeat transmembrane neuronal 3 antibody, LRRTM3 antibody, lrrtm3 antibody, Lrrtm3 antibody
- 背景
- LRRTM3 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Abeta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.
- 基因ID
- 347731
- NCBI登录号
- NP_821079
- UniProt
- Q86VH5
- 途径
- Synaptic Membrane
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