At least two isoforms of ZBTB6 are known to exist, this antibody will only recognize the shorter isoform. This antibody is predicted to not cross-react with other ZBTB protein family members.
纯化方法
ZBTB6 Antibody is affinity chromatography purified via peptide column.
免疫原
ZBTB6 antibody was raised against a 15 amino acid synthetic peptide near the center of human ZBTB6. The immunogen is located within amino acids 180 - 230 of ZBTB6.
ZBTB6 antibody can be used for detection of ZBTB6 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
ZBTB6 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
ZBTB6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
ZBTB6
(Zinc Finger and BTB Domain Containing 6 (ZBTB6))
别名
ZBTB6
背景
ZBTB6 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB6, also known as ZNF482, is highly expressed in brain. While little is known about ZBTB6, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB family member, ZBTB5, also acts as a transcriptional repressor, and can interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, suggesting that ZBTB6 may also act as a transcriptional repressor.