ZBTB5 抗体 (C-Term)
Quick Overview for ZBTB5 抗体 (C-Term) (ABIN6991469)
抗原
See all ZBTB5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- At least two isoforms of ZBTB5 are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.
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纯化方法
- ZBTB5 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ZBTB5 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ZBTB6. The immunogen is located within the last 50 amino acids of ZBTB5.
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亚型
- IgG
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anti-Zinc Finger and BTB Domain Containing 5 (ZBTB5) (AA 581-677) antibody
ZBTB5 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 5 (ZBTB5) (AA 178-206), (N-Term) antibodyZBTB5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB26523 unconjugated
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应用备注
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ZTBT5 antibody can be used for detection of ZTBT5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ZBTB5 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ZBTB5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))
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别名
- ZBTB5
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背景
- ZBTB5 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.
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基因ID
- 9925
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NCBI登录号
- NP_055687
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UniProt
- O15062
抗原
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