SYNPO 抗体 (C-Term)
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Quick Overview for SYNPO 抗体 (C-Term) (ABIN6991442)
抗原
See all SYNPO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- At least three isoforms of SYNPO are known to exist, this antibody will detect all three isoforms. SYNPO antibody is predicted to not cross-react with other SYNPO family member proteins.
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纯化方法
- SYNPO Antibody is affinity chromatography purified via peptide column.
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免疫原
- SYNPO antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SYNPO. The immunogen is located within the last 50 amino acids of SYNPO.
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亚型
- IgG
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应用备注
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SYNPO antibody can be used for detection of SYNPO by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SYNPO Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SYNPO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SYNPO (Synaptopodin (SYNPO))
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别名
- SYNPO
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背景
- SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
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分子量
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Predicted: 75, 99, 102 kDa
Observed: 95 kDa -
基因ID
- 11346
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NCBI登录号
- NP_001159680
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UniProt
- Q8N3V7
抗原
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