PAPPA2 抗体 (N-Term)
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北京 101111
Quick Overview for PAPPA2 抗体 (N-Term) (ABIN6991429)
抗原
See all PAPPA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-500, N-Term
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纯化方法
- PLAC3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PLAC3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human PLAC3. The immunogen is located within amino acids 450 - 500 of PLAC3.
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亚型
- IgG
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应用备注
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PLAC3 antibody can be used for detection of PLAC3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PLAC3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PLAC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PAPPA2 (Pappalysin 2 (PAPPA2))
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别名
- PLAC3
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背景
- PLAC3 Antibody: PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.
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基因ID
- 60676
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NCBI登录号
- NP_064714
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UniProt
- Q9BXP8
抗原
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