TRIP6 抗体 (AA 190-240)
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北京 101111
Quick Overview for TRIP6 抗体 (AA 190-240) (ABIN6991423)
抗原
See all TRIP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 190-240
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纯化方法
- TRIP6 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TRIP6 antibody was raised against a 15 amino acid synthetic peptide near the center of human TRIP6. The immunogen is located within amino acids 190 - 240 of TRIP6.
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亚型
- IgG
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应用备注
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TRIP6 antibody can be used for detection of TRIP6 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TRIP6 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TRIP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))
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别名
- TRIP6
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背景
- TRIP6 Antibody: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-κ,B activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.
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基因ID
- 7205
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NCBI登录号
- NP_003293
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UniProt
- Q15654
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途径
- Cell-Cell Junction Organization
抗原
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