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KPNA4 抗体 (N-Term)

This anti-KPNA4 antibody is a 兔 多克隆 antibody detecting KPNA4 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991416
发货至: 中国

Quick Overview for KPNA4 抗体 (N-Term) (ABIN6991416)

抗原

See all KPNA4 抗体
KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This KPNA4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
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    AA 30-80, N-Term

    纯化方法

    KPNA4 Antibody is affinity chromatography purified via peptide column.

    免疫原

    KPNA4 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA4. The immunogen is located within amino acids 30 - 80 of KPNA4.

    亚型

    IgG
  • 应用备注

    KPNA4 antibody can be used for detection of KPNA4 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    KPNA4 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    KPNA4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

    别名

    KPNA4

    背景

    KPNA4 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers. KPNA3 has been shown to be important in the TNF-α,-induced nuclear import of NF-κ,B. It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in both dividing and non-dividing cells.

    基因ID

    3840

    UniProt

    O00629

    途径

    Protein targeting to Nucleus
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