BANP 抗体 (AA 300-350)
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北京 101111
Quick Overview for BANP 抗体 (AA 300-350) (ABIN6991411)
抗原
See all BANP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-350
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纯化方法
- BANP Antibody is affinity chromatography purified via peptide column.
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免疫原
- BANP antibody was raised against a 14 amino acid synthetic peptide near the center of human BANP. The immunogen is located within amino acids 300 - 350 of BANP.
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亚型
- IgG
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anti-Protein BANP (BANP) (AA 1-260) antibody
BANP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein BANP (BANP) (AA 1-469) antibodyBANP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein BANP (BANP) (AA 30-390) antibodyBANP 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1524CT337-6-32 unconjugated
anti-Protein BANP (BANP) antibodyBANP 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated
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应用备注
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BANP antibody can be used for detection of BANP by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- BANP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- BANP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BANP (Protein BANP (BANP))
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别名
- BANP
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背景
- BANP Antibody: BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen. BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest. p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop. BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling. Furthermore, BANP can modulate NF-κ,B transactivation and can inhibit tumorigenesis by regulating NF-κ,B target genes. Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix.
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基因ID
- 54971
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NCBI登录号
- NP_001167014
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UniProt
- Q8N9N5
抗原
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