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NLRP10 抗体 (N-Term)

This anti-NLRP10 antibody is a 兔 多克隆 antibody detecting NLRP10 in ELISA, WB, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6991406
发货至: 中国

Quick Overview for NLRP10 抗体 (N-Term) (ABIN6991406)

抗原

See all NLRP10 抗体
NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

适用

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宿主

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克隆类型

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多克隆

标记

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This NLRP10 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    纯化方法

    NALP10 Antibody is affinity chromatography purified via peptide column.

    免疫原

    NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10. The immunogen is located within the first 50 amino acids of NALP10.

    亚型

    IgG
  • 应用备注

    NALP10 antibody can be used for detection of NALP10 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    NALP10 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    NALP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

    别名

    NALP10

    背景

    NALP10 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1β, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1β, processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.

    基因ID

    338322

    NCBI登录号

    NP_789791

    UniProt

    Q86W26

    途径

    Inflammasome
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