NLRP10 抗体 (N-Term)
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北京 101111
Quick Overview for NLRP10 抗体 (N-Term) (ABIN6991406)
抗原
See all NLRP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- NALP10 Antibody is affinity chromatography purified via peptide column.
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免疫原
- NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10. The immunogen is located within the first 50 amino acids of NALP10.
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亚型
- IgG
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应用备注
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NALP10 antibody can be used for detection of NALP10 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NALP10 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NALP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
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别名
- NALP10
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背景
- NALP10 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1β, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1β, processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.
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基因ID
- 338322
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NCBI登录号
- NP_789791
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UniProt
- Q86W26
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途径
- Inflammasome
抗原
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