NLRP5 抗体 (C-Term)
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Quick Overview for NLRP5 抗体 (C-Term) (ABIN6991402)
抗原
See all NLRP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- NALP5 Antibody is affinity chromatography purified via peptide column.
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免疫原
- NALP5 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human NALP5. The immunogen is located within the last 50 amino acids of NALP5.
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亚型
- IgG
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anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (AA 157-256) antibody
NLRP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (C-Term) antibodyVerified NLRP5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (AA 121-170) antibodyNLRP5 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (N-Term) antibodyNLRP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (N-Term) antibodyNLRP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (C-Term) antibodyNLRP5 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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NALP5 antibody can be used for detection of NALP5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NALP5 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NALP5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))
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别名
- NALP5
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背景
- NALP5 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
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基因ID
- 126206
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NCBI登录号
- NP_703148
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UniProt
- P59047
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途径
- Inflammasome
抗原
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