NLRP4 抗体 (AA 330-380)
This anti-NLRP4 antibody is a 兔 多克隆 antibody detecting NLRP4 in ELISA 和 WB. Suitable for 人 和 小鼠.
Quick Overview for NLRP4 抗体 (AA 330-380) (ABIN6991401)
抗原
See all NLRP4 抗体
NLRP4
(NLR Family, Pyrin Domain Containing 4 (NLRP4))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This NLRP4 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 330-380
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纯化方法
- NALP4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- NALP4 antibody was raised against a 13 amino acid synthetic peptide near the center of human NALP4. The immunogen is located within amino acids 330 - 380 of NALP4.
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亚型
- IgG
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anti-NLR Family, Pyrin Domain Containing 4 (NLRP4) (AA 351-450) antibody
NLRP4 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 4 (NLRP4) (AA 121-149) antibodyNLRP4 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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NALP4 antibody can be used for detection of NALP4 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NALP4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NALP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NLRP4 (NLR Family, Pyrin Domain Containing 4 (NLRP4))
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别名
- NALP4
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背景
- NALP4 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP4, also known as PYRIN-containing APAF1-like protein 4, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. In transfected 293 cells, NALP4 suppressed NF-κ,B induction by TNF-α, and IL-1β, suggesting NALP4 operates at a point of convergence in these two signaling pathways. NALP4 also suppressed NF-κ,B induction resulting from overexpression of several adapter proteins and protein kinases involved in these pathways, including TRAF2, TRAF6, RIP, and IRAK2, as well as the IKK-alpha and IKK-beta, suggesting that NALP4 is critical in modulating NF-κ,B activity.
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基因ID
- 147945
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UniProt
- Q96MN2
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途径
- Inflammasome
抗原
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